Who Has The Best Chance Of Winning March Madness 2025. The duke blue devils open as the favorites to win the 2025 ncaa tournament, according to the march madness 2025 odds released by our best march madness betting sites ahead of monday's. Here are college basketball odds for the 2025 men's ncaa tournament championship at draftkings sportsbook:
Duke (+1000) draftkings sportsbook โข wager: +950 (bet $10 to win $105 total) gonzaga: